uname@mname ~ $ emerge -avuDN @world 

Local copy of remote index is up-to-date and will be used.
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Local copy of remote index is up-to-date and will be used.

These are the packages that would be merged, in order:

Calculating dependencies... done!

Total: 0 packages, Size of downloads: 0 KiB

WARNING: One or more updates/rebuilds have been skipped due to a dependency conflict:

dev-python/setuptools:0

  (dev-python/setuptools-50.3.0:0/0::gentoo, ebuild scheduled for merge) USE="-test" ABI_X86="(64)" PYTHON_TARGETS="python3_7 python3_8 (-pypy3) -python3_6 -python3_9" conflicts with
    dev-python/setuptools[python_targets_python2_7(-),-python_single_target_python2_7(-)] required by (dev-python/sudsds-1.0.1-r1:0/0::calculate, installed) USE="-doc" ABI_X86="(64)" PYTHON_TARGETS="python2_7"
                                                                                         
    dev-python/setuptools[python_targets_python2_7(-),-python_single_target_python2_7(-)] required by (dev-python/cryptography-python2-2.9-r2:0/0::calculate, installed) USE="-idna -libressl -test" ABI_X86="(64)" PYTHON_TARGETS="python2_7"
                                                                                         
    >=dev-python/setuptools-42.0.2[python_targets_python2_7(-),-python_single_target_python2_7(-)] required by (dev-python/cffi-python2-1.14.0-r3:0/1.14.0::calculate, installed) USE="-doc -test" ABI_X86="(64)" PYTHON_TARGETS="python2_7"
                                                                                                  

dev-python/certifi:0

  (dev-python/certifi-10001-r1:0/0::gentoo, ebuild scheduled for merge) USE="-test" ABI_X86="(64)" PYTHON_TARGETS="python3_7 python3_8 (-pypy3) -python3_6 -python3_9" conflicts with
    >=dev-python/certifi-2016.9.26[python_targets_python2_7(-),python_targets_python3_7(-),python_targets_python3_8(-),-python_single_target_pypy3(-),-python_single_target_python2_7(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),-python_single_target_python3_9(-)] required by (dev-python/setuptools-46.4.0-r3:0/0::gentoo, installed) USE="-test" ABI_X86="(64)" PYTHON_TARGETS="python2_7 python3_7 python3_8 (-pypy3) -python3_6 -python3_9"
                                                                                                                                                                                                                                                                                                                                     

uname@mname ~ $ #-----------------------------
uname@mname ~ $ sudo emerge --update --newuse --deep @world
Password: 

Local copy of remote index is up-to-date and will be used.

Local copy of remote index is up-to-date and will be used.
Calculating dependencies... done!

WARNING: One or more updates/rebuilds have been skipped due to a dependency conflict:

dev-python/setuptools:0

  (dev-python/setuptools-50.3.0:0/0::gentoo, ebuild scheduled for merge) USE="-test" ABI_X86="(64)" PYTHON_TARGETS="python3_7 python3_8 (-pypy3) -python3_6 -python3_9" conflicts with
    >=dev-python/setuptools-42.0.2[python_targets_python2_7(-),-python_single_target_python2_7(-)] required by (dev-python/cffi-python2-1.14.0-r3:0/1.14.0::calculate, installed) USE="-doc -test" ABI_X86="(64)" PYTHON_TARGETS="python2_7"
                                                                                                  
    dev-python/setuptools[python_targets_python2_7(-),-python_single_target_python2_7(-)] required by (dev-python/cryptography-python2-2.9-r2:0/0::calculate, installed) USE="-idna -libressl -test" ABI_X86="(64)" PYTHON_TARGETS="python2_7"
                                                                                         
    dev-python/setuptools[python_targets_python2_7(-),-python_single_target_python2_7(-)] required by (dev-python/sudsds-1.0.1-r1:0/0::calculate, installed) USE="-doc" ABI_X86="(64)" PYTHON_TARGETS="python2_7"
                                                                                         

dev-python/certifi:0

  (dev-python/certifi-10001-r1:0/0::gentoo, ebuild scheduled for merge) USE="-test" ABI_X86="(64)" PYTHON_TARGETS="python3_7 python3_8 (-pypy3) -python3_6 -python3_9" conflicts with
    >=dev-python/certifi-2016.9.26[python_targets_python2_7(-),python_targets_python3_7(-),python_targets_python3_8(-),-python_single_target_pypy3(-),-python_single_target_python2_7(-),-python_single_target_python3_6(-),-python_single_target_python3_7(-),-python_single_target_python3_8(-),-python_single_target_python3_9(-)] required by (dev-python/setuptools-46.4.0-r3:0/0::gentoo, installed) USE="-test" ABI_X86="(64)" PYTHON_TARGETS="python2_7 python3_7 python3_8 (-pypy3) -python3_6 -python3_9"
                                                                                                                                                                                                                                                                                                                                     

>>> Jobs: 0 of 0 complete                           Load avg: 3.51, 1.94, 1.45
>>> Auto-cleaning packages...

>>> No outdated packages were found on your system.

uname@mname ~ $